[Pd(μ-Cl)Cl(IPr*)]2: a highly hindered pre-catalyst for the synthesis of tetra-ortho-substituted biaryls via Grignard reagent cross-coupling.

نویسندگان

  • Mathieu Lesieur
  • Alexandra M Z Slawin
  • Catherine S J Cazin
چکیده

The new well-defined catalyst [Pd(μ-Cl)Cl(IPr*)]2 enables the efficient Grignard reagent cross-coupling for the synthesis of tetra-ortho-substituted biaryls. The high reactivity of the complex is associated with the important bulkiness of the IPr* ligand. The dimer represents the most efficient catalyst reported to date for this challenging transformation.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 12 30  شماره 

صفحات  -

تاریخ انتشار 2014